what are the clinical features of Parkinson’s disease? Blue Cross brain Hospital of Shanghai expert Chen Hongyao Professor Parkinson’s disease, Parkinson’s disease is the clinical characteristics of slow, static tremor, gear-like muscle hypertonia and abnormal postural reflex. Usually in 40-70 disease, 60 years of age to heights. Symptoms gradually increase 10-20 year, pathology is the cerebral basal dopaminergic neurons of the substantia nigra is missing relevant. Below, we detail the clinical features of Parkinson’s disease.
Blue Cross brain Hospital of Shanghai of Parkinson’s disease expert says Chen Hongyao, early manifestations in patients with Parkinson’s disease such as tremors, the glass in one hand tremors reduced or disappear when the purposive activity, System button fine motor difficulties are divided into five periods:
1 demonstrated by the involvement of limbs on one side, Involvement of the upper limb in half flexion, the body to not suffer lateral tilt;
2 bilateral involvement early in the period of postural changes, slow to panic and gait, reduced lower limb activities, significant
3 period in gait abnormality, functional disorder, postural instability, and easily falls;
4 significant impairment, can only walk with the help of;
In patients with total disability,
5 confined to beds or wheelchairs, or with the help of standing or walking.
non-exercise-induced symptoms include Seborrheic Dermatitis, hyposmia, sleep difficulties, sleep maintenance difficulties, 30% of lower limbs during sleep in patients with paroxysmal movement. Autonomic nervous dysfunction: orthostatic hypotension and gastrointestinal motility disorders, urinary bladder dysfunction, thermoregulation disorder, female sexual dysfunction. Dysphagia normally appear in the advanced, the original pharyngeal esophageal motor disorders.
often accompanied by mental and cognitive disorders: 40% depression experience prior to movement disorders; 40% are anxiety, hallucinations (Visual hallucinations, mostly non-threatening), mental disorders, vivid sleepwalking is common in the late stage of the disease. Cognitive impairment is often as a subcortical dementia, typical performance is late.
Blue Cross brain Hospital of Shanghai expert neural nuclei of radiofrequency ablation for fundamentally overcome the drawbacks of the traditional surgery. Surgery for patients with Stereotactic head frame placement using advanced positioning technologies, can accurately detect exactly where the abnormal activity of brain cells, and then using computer programming of radio-frequency heating method to eliminate these cells. His accuracy from the traditional operation of visible to the naked eye cm hundred microns of orders of magnitude to the cell level orders of magnitude, and in theory will fall to zero in the incidence of major complications.. The revolutionary progress made surgery again to the frontier zone of the treatment of Parkinson’s disease.